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FLASH GENE

Symbol

ZNF200

contributors: npt - updated : 06-05-2009

HGNC name	zinc finger protein 200
HGNC id	12993

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

Location	16p13.3      Physical location : 3.272.324 - 3.285.457
Synonym symbol(s)	MGC45293, ZNFMF

DNA

TYPE	functioning gene
STRUCTURE	13.07 kb     5 Exon(s)

10 Kb 5' upstream gene genomic sequence study

MAPPING

cloned

Y

linked

N

status

confirmed

RNA

TRANSCRIPTS	type	messenger

text	variants 4,5 and 6 encode the same isoform and variants 1 and 2 encode the same isoform

identification nb exons type bp product Protein kDa AA specific expression Year Pubmed variant 4 - - 3179 45.3 394 - Nishida (2007) variant 5 - - 3384 45.3 394 - Nishida (2007) variant 6 - - 3303 45.3 394 - Nishida (2007) variant 1 5 - 3387 45.4 395 - Nishida (2007) variant 3 5 - 3179 variant 2 5 - 3306 45.4 395 - Nishida (2007)

EXPRESSION

Type	ubiquitous

constitutive of

expressed in	(based on citations)
organ(s)	System Organ level 1 Organ level 2 Organ level 3 Organ level 4 Level Pubmed Species Stage Rna symbol Reproductive male system testis     predominantly

cell lineage

cell lines

fluid/secretion

at STAGE

PROTEIN

PHYSICAL PROPERTIES

STRUCTURE

motifs/domains	a N terminal Krüppel-associated box (KRAB)
	five C(2)H(2)-type zinc finger domains (Nishida 2007)

conjugated

MetalloP

HOMOLOGY

Homologene

FAMILY	krueppel C2H2-type zinc-finger protein family
	KRAB subfamily

CATEGORY

transcription factor

SUBCELLULAR LOCALIZATION	intracellular
	intracellular,nucleus,chromatin/chromosome

basic FUNCTION

transcriptional regulator

CELLULAR PROCESS

nucleotide, transcription

PHYSIOLOGICAL PROCESS

PATHWAY

metabolism

signaling

a component

INTERACTION

DNA

binding

RNA

small molecule	metal binding,
	Zn2+

protein

binding partner of EHMT2 (Nishida 2007)

cell & other

REGULATION

ASSOCIATED DISORDERS

ANIMAL & CELL MODELS