basic FUNCTION
| might be involved in the progression of atherosclerosis in aorta  |
|
angiogenic factor that can modulate angiogenic growth factor activity and angiogenesis |
|
potentiates responses to mitogenic and angiogenic factors including FGF and VEGF  |
|
might associated with pulmonary function by playing an important role in the determination of FEV (ETS oncogene family) and FVC  |
|
promotes keratinocyte attachment and migration and acts as a regulator of cell-matrix interactions  |
|
a role for Smoc-2 in growth control, activation of Integrin-Linked Kinase (ILK) and cyclin D1 expression  |
|
a role in cell cycle by maintaining ILK activity during G1 and involved in mediating the mitogenic and angiogenic |
|
effects of growth factors such as VEGF, PDGF, and FGF  |
|
exhibits pro-angiogenic properties and stimulates cell cycle progression via integrin-linked kinase  |
|
a novel transcriptional target of activated Aryl-hydrocarbon receptor (Ahr), has a possible role in embryonic gonad development  |
|
with SMOC1 are matricellular proteins thought to influence growth factor signaling, migration, proliferation, and angiogenesis  |
|
may mediate intercellular signaling and cell type-specific differentiation during gonad and reproductive tract development  |
|
regulate interactions between cells and the extracellular matrix  |
|
potential role in linking the extracellular matrix with the intracellular effector ILK  |
|
particularly important for dental development but does not play a major role in eye and limb development  |