basic FUNCTION
| insulin regulated facilitative glucose transporter |
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transport facilitator playing a major role in the fuel supply of mature spermatozoa, and is a potential target for inhibition of sperm cell function |
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class 3 sugar transport facilitator, not playing a significant role for maintenance of whole body glucose homeostasis |
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plays an important role in the energy metabolism of sperm cells |
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potential role in the so far unexplored substrate transport across intracellular membranes |
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activities of the enigmatic transporters SLC2A8 and SLC2A11 are required for proliferation and viability in myeloma, albeit because of functionalities probably distinct from whole-cell glucose supply |
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is a facilitative glucose and fructose transporter |
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is essential for hepatocyte fructose transport and fructose-induced macrosteatosis |
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SLC2A4 and SLC2A8 trafficking is impaired in the diabetic atria and rescued by insulin treatment |
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is likely a mammalian trehalose transporter required for hepatocyte trehalose-induced autophagy and signal transduction |
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SLC2A1 and SLC2A8 both transporters are involved in glucose uptake into cis-Golgi, supporting lactose synthesis |