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FLASH GENE
Symbol SLC20A2 contributors: mct - updated : 11-12-2013
HGNC name solute carrier family 20 (phosphate transporter), member 2
HGNC id 10947
Corresponding disease
BGCI1 basal ganglia cancification, idiopathic, 1
Location 8p11.21      Physical location : 42.273.994 - 42.397.068
Synonym name
  • gibbon ape leukemia virus receptor 2, Moloney murine leukemia virus receptor
  • murine leukemia virus, amphotropic, receptor
  • type III sodium-dependent phosphate transporter 2
  • Synonym symbol(s) D8S1915, GLVR2, MLVAR, PIT2, GLVR-2, IBGC1, IBGC3, PIT-2, RAM1
    DNA
    TYPE functioning gene
    STRUCTURE 123.38 kb     11 Exon(s)
    10 Kb 5' upstream gene genomic sequence study
    MAPPING cloned Y linked   status provisional
    Physical map
    FLJ13842 8p11.21 hypothetical protein FLJ13842 SFRP1 8p12-p11.2 secreted frizzled-related protein 1 GCP16 LOC392214 8 similar to Keratin, type I cytoskeletal 18 (Cytokeratin 18) (K18) (CK 18) MGC14799 8p11.21 hypothetical protein MGC14799 DKFZp586M1819 8p11.21 putative lysophosphatidic acid acyltransferase FLJ25169 8p11.21 hypothetical protein FLJ25169 ANK1 8p11.2 ankyrin 1, erythrocytic MYST3 8p11 MYST histone acetyltransferase (monocytic leukemia) 3 AP3M2 8p11.2 adaptor-related protein complex 3, mu 2 subunit PLAT 8p12-p11.2 plasminogen activator, tissue LOC389650 8 LOC389650 IKBKB 8p11.2 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta POLB 8p11.2 polymerase (DNA directed), beta DKK4 8p11.2-p11.1 dickkopf homolog 4 (Xenopus laevis) VDAC3 8q11.2 voltage-dependent anion channel 3 SLC20A2 8p12-q21 solute carrier family 20 (phosphate transporter), member 2 LOC114926 8p11.21 hypothetical protein BC013035 CHRNB3 8p11.2 cholinergic receptor, nicotinic, beta polypeptide 3 CHRNA6 8p22 cholinergic receptor, nicotinic, alpha polypeptide 6 THAP1 8p11.1 THAP domain containing, apoptosis associated protein 1 DKFZP564A022 8p11.21 hypothetical protein DKFZp564A022 HOOK3 8p11.21 hook homolog 3 (Drosophila) FNTA 8p22-q11 farnesyltransferase, CAAX box, alpha FLJ23356 8p11.21 hypothetical protein FLJ23356 FLJ32731 8p11.1 hypothetical protein FLJ32731 LOC347028 8p11.21 similar to AFG3-like protein 2 (Paraplegin-like protein) LOC340441 8p11.21 similar to pote protein; Expressed in prostate, ovary, testis, and placenta LOC389651 8 similar to hypothetical protein (L1H 3 region) - human
    RNA
    TRANSCRIPTS type messenger
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    11 - 3971 - 652 - 2010 20817733
    11 - 3639 - 652 - 2010 20817733
    11 - 4008 - 652 - 2010 20817733
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivemouth   highly
    Nervousbrain   highly
    Respiratoryrespiratory tractlarynx  highly
     respiratory tracttrachea  highly
    Urinarykidneytubuleconvoluted tubuleproximal tubule  Rattus norvegicus
    cells
    SystemCellPubmedSpeciesStageRna symbol
    Urinaryepithelial cell Rattus norvegicus
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
    HOMOLOGY
    interspecies homolog to murine Slc20a2
    Homologene
    FAMILY phosphatase transporter family, PiT family
    CATEGORY unknown/unspecified , receptor , transport channel
    SUBCELLULAR LOCALIZATION     plasma membrane
    basic FUNCTION
  • transporter capable of Na(+)-independent P(i) transport at acidic pH
  • modify its oligomerization independently of Pi (inorganic phosphate) uptake in response to changes in the extracellular Pi concentration, suggesting a possible role in Pi sensing
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
  • receptor for amphotropic murine leukemia virus (A-MuLV) and 10A1 MuLV
  • NELL1 increases pre-osteoblast mineralization using both phosphate transporter SLC20A1, SLC20A2
  • cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) BGCI1
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS