Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol RMND1 contributors: mct - updated : 17-11-2012
HGNC name required for meiotic nuclear division 1 homolog (S. cerevisiae)
HGNC id 21176
Corresponding disease
COXPD11 combined oxidative phosphorylation deficiency 11
Location 6q25.1      Physical location : 151.725.988 - 151.773.316
Synonym name
  • chromosome 6 open reading frame 96
    • Synonym symbol(s) bA351K16.3, FLJ20627, C6orf96, RMD1, COXPD11, MGC117362, MGC149570, MGC88260
    DNA
    TYPE functioning gene
    STRUCTURE 47.33 kb     12 Exon(s)
    MAPPING cloned   linked   status
    RNA
    TRANSCRIPTS type
    identificationnb exonstypebpproduct
    ProteinkDaAAspecific expressionYearPubmed
    12 - 1928 - 449 - 2012 23022098
    EXPRESSION
    Type ubiquitous
       expressed in (based on citations)
    organ(s)
    SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
    Digestivepharynx   highly
    Endocrineadrenal gland   highly
    Lymphoid/Immunetonsils   highly
    cell lineage
    cell lines
    fluid/secretion
    at STAGE
    PROTEIN
    PHYSICAL PROPERTIES
    STRUCTURE
    motifs/domains
  • a mitochondrial localization signal at the N terminus
  • a coiled-coil domain
  • a transmembrane domain at the extreme C terminus
    • HOMOLOGY
    Homologene
    FAMILY SIF2 family, an evolutionary conserved family of proteins
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    text
  • localizes to mitochondria
    • basic FUNCTION
  • RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of a large mitochondrial-membrane complex that is required for the translation of the mitochondrially encoded polypeptides and is thus essential for the biogenesis of the OXPHOS complexes
    • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) COXPD11
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS