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FLASH GENE
Symbol RMND1 contributors: mct - updated : 17-11-2012
HGNC name required for meiotic nuclear division 1 homolog (S. cerevisiae)
HGNC id 21176
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrineadrenal gland   highly
Lymphoid/Immunetonsils   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a mitochondrial localization signal at the N terminus
  • a coiled-coil domain
  • a transmembrane domain at the extreme C terminus
  • HOMOLOGY
    Homologene
    FAMILY SIF2 family, an evolutionary conserved family of proteins
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    text
  • localizes to mitochondria
  • basic FUNCTION
  • RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of a large mitochondrial-membrane complex that is required for the translation of the mitochondrially encoded polypeptides and is thus essential for the biogenesis of the OXPHOS complexes
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) COXPD11
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS