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FLASH GENE
Symbol RMND1 contributors: mct - updated : 17-11-2012
HGNC name required for meiotic nuclear division 1 homolog (S. cerevisiae)
HGNC id 21176
RNA
TRANSCRIPTS type
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
12 - 1928 - 449 - 2012 23022098
EXPRESSION
Type ubiquitous
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Digestivepharynx   highly
Endocrineadrenal gland   highly
Lymphoid/Immunetonsils   highly
cell lineage
cell lines
fluid/secretion
at STAGE
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • a mitochondrial localization signal at the N terminus
  • a coiled-coil domain
  • a transmembrane domain at the extreme C terminus
  • HOMOLOGY
    Homologene
    FAMILY SIF2 family, an evolutionary conserved family of proteins
    CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm,organelle,mitochondria
    text
  • localizes to mitochondria
  • basic FUNCTION
  • RMND1 complex is necessary for mitochondrial translation, possibly by coordinating the assembly or maintenance of the mitochondrial ribosome
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
  • part of a large mitochondrial-membrane complex that is required for the translation of the mitochondrially encoded polypeptides and is thus essential for the biogenesis of the OXPHOS complexes
  • INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    corresponding disease(s) COXPD11
    Susceptibility
    Variant & Polymorphism
    Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS