basic FUNCTION
| colony-stimulating factor (multilineage) |
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survival factor inducing phosphorylation of BAD through the activation of the protein kinases (AKT1, AKT2) |
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IL3 and KITLG have synergistic effects with EPO on the proliferation, differentiation and apoptosis of erythroid progenitors ![](pubmed.jpg) |
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induces a PIM1-dependent antiapoptotic pathway in primary human basophils ![](pubmed.jpg) |
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strong regulator of hematopoiesis, also potentially playing an important role in inhibition of TNF-alpha-induced bone resorption ![](pubmed.jpg) |
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promotes the survival and growth of multipotent hematopoietic progenitors and stimulates myelopoiesis ![](pubmed.jpg) |
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cytokine secreted by activated T lymphocytes, stimulates the proliferation, differentiation and survival of pluripotent hematopoietic stem cells ![](pubmed.jpg) |
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irreversibly inhibits TNFRSF11A expression that results in inhibition of important signaling molecules induced by TNFSF11 ![](pubmed.jpg) |
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required for maintenance of many hematopoietic cell lines, such as BaF3 ![](pubmed.jpg) |
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is an important cytokine that regulates hematopoiesis ![](pubmed.jpg) |
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in a dose-dependent manner increases osteoblast differentiation and matrix mineralization in human mesenchymal stem cells (MSCs) ![](pubmed.jpg) |
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has a potential as an anabolic agent for stimulation of bone formation in important bone diseases ![](pubmed.jpg) |