Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | IARS | contributors: mct - updated : 16-09-2016 |
HGNC name | isoleucine-tRNA synthetase |
HGNC id | 5330 |
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Corresponding disease |
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Location | 9q22.31 Physical location : 94.972.624 - 95.056.038 | ||
Synonym name | isoleucine tRNA ligase 1, cytoplasmic | ||
Synonym symbol(s) | ILRS, ISM1, FLJ20736, IARS1, PRO0785 | ||
EC.number | 6.1.1.5 |
DNA |
TYPE | functioning gene |
STRUCTURE | 83.55 kb 34 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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text | two alternatively spliced variants (5'utr) |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
|
HOMOLOGY |
interspecies | homolog to C.elegans rha8.6 |
Homologene |
FAMILY | class 1 aminoacyl tRNA synthetase family |
CATEGORY | enzyme |
SUBCELLULAR LOCALIZATION | plasma membrane |
intracellular | |
intracellular,cytoplasm,cytosolic | |
intracellular,nucleus,nucleoplasm |
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | GRIDHH |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |