basic FUNCTION
| 5-hydroxytryptamine (serotonin) receptor, activating adenylate cyclase |
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biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen |
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could reside in different dimeric contexts and initiate different signaling pathways, depending on the neuronal circuitry and/or brain region |
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involved in a wide variety of central nervous system (CNS) functions, namely circadian rhythm, depression, thermoregulation, obsessive-compulsive disorder (OCD), anxiety |
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regulated expression of HTR7 and GNA12-protein may represent a molecular mechanism by which serotonin specifically modulates formation of initial neuronal networks during early postnatal development |
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might play a crucial role in shaping neuronal morphology and behaviorally relevant neuronal networks, paving the way to new approaches able to modulate CNS connectivity |
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critical role in immune response and inflammation in the gut |