protein
| cyclin E ( |
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E2F transcription factor 1, E2F1 ( |
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kinase-associated phosphatase, KAP ( |
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cyclin-dependent kinase interactor 1, Cdi1 ( |
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CksHs1 ( |
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Cdc25 ( |
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cyclin A ( |
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Lyn tyrosine kinase ( |
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p130 ( |
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BRCA1a and BRCA1b ( |
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H-1 kinase ( |
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pol delta ( |
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NF-kappa B ( |
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cyclin E2 ( |
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cell division cycle 6 homolog (S. cerevisiae), CDC6 ( |
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p38 mitogen-activated protein kinase ( |
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TOK-1alpha ( |
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proliferating cell nuclear antigen, PCNA ( ) |
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p12(DOC-1) ( |
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protein kinase C eta, PKCeta ( |
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HIR histone cell cycle regulation defective homolog A (S. cerevisiae), HIRA ( |
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Cyclin A1 ( |
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CDK-interacting protein phosphatase KAP ( |
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transcription factor CCAAT/enhancer binding protein alpha, C/EBPalpha ( |
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Speedy, Spy1 ( |
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Cyclin B3, CCNB3 ( |
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INCA1, KARCA1, PROCA1, GPS2, Ku70, receptor for activated protein kinase C1/guanine nucleotide-binding protein beta-2-like-1, and RBM4 ( |
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NIRF ( |
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Smad3 ( |
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human O(6)-methylguanine-DNA methyltransferase, MGMT ( |
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PURA |
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ANKRD17 |
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CCNE2-CDK2 activation by estrogen occurs via E2F- and CHD8-mediated transcription of CCNE2 downstream of CCND1 |
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KAT2B directly interacts with CDK2 (this interaction is mainly produced during S and G(2)/M phases of the cell cycle) |
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phosphorylating USP37, and stimulating its full activity |
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as cells progress through S phase, CCNA2 initially forms complexes with CDK2, and, later, most CCNA2 molecules are bound to CDK1 |
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through activation of a centrosomal pool of CDK2, CDC25B stabilises the local pool of Monopolar spindle 1 (Mps1) which in turn regulates the level of CETN2 at the centrosome |
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CDK2 negatively regulates the stability and activity of FOXP3 and implicate CDK-coupled receptor signal transduction in the control of regulatory T cell function and stability |
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CDK2AP1 suppresses cell growth, differentiation and angiogenesis in numerous types of carcinoma by interacting with certain cell cycle proteins, including CDK2 |
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interaction of MYBBP1A with CDK2 and TPP2, to form a protein-protein interaction network |
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HOXA7 stimulates human hepatocellular carcinoma proliferation through CCNE1/CDK2 |
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CIZ1 is a nuclear matrix protein that cooperates with cyclin A2 (encoded by CCNA2) and CDK2 to promote mammalian DNA replication |
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CDK2 phosphorylation regulates the protein stability of KLF10 by interfering with binding of the E3 ligase SIAH1 |
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CCP110 is a critical mediator of CDK2 inhibition-driven anaphase catastrophe |
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in addition to drive cell cycle progression, CDK2 also targets RNF4, which is involved in the regulatory network of DSBs repair |
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PLA2G4A acts as a bridge in the formation of a multiprotein complex at the G2-to-M transition to promote binding of SIRT2 to CCNA2-CDK2 |
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CIAPIN1 played an important role in the proliferation of liver cancer cells through increasing the expressions of cell cycle related proteins CCND1, CDK2, CDK4, and CCNE1 |
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CCNK-dependent, novel phosphorylation site in CCNE1 that disrupts its interaction with CDK2 |
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CDK2 can bind to the promoters of a number of genes in male germ cells including that of EHMT1 through interaction with the NRF1 transcription factor |
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CDK2 regulates the NRF1/ EHMT1 axis during meiotic prophase I |