| 1 | CDK2, SEPTIN2
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| Coupling function of cyclin-dependent kinase 2 and Septin2 in the promotion of hepatocellular carcinoma.
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| Xu C, Zhang W, Zhang X, Zhou D, Qu L, Liu J, Xiao M, Ni R, Jiang F, Ni W, Lu C.
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| Cancer Sci 110(2):540-549. doi: 10.1111/cas.13882. Epub 2018 Dec 26.
2019
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| 2 | CDK2, EHMT1, NRF1
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| CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I.
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| Palmer N, Talib SZA, Ratnacaram CK, Low D, Bisteau X, Lee JHS, Pfeiffenberger E, Wollmann H, Tan JHL, Wee S, Sobota R, Gunaratne J, Messerschmidt DM, Guccione E, Kaldis P.
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| J Cell Biol. Sep 2;218(9):2896-2918. doi: 10.1083/jcb.201903125. Epub 2019 Jul 26. 2019
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| 3 | CCNE2, CCNK, CDK2
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| Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation.
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| Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, Dai Q, Zhang Y, Min L, Li Q, Yin R, Ding P, Li N, Qu Y, Mu D, Qin J, Zhu X, Xiao ZX, Li Q.
|
| Nat Commun 9(1):1876. doi: 10.1038/s41467-018-04258-w.
2018
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| 4 | CCND1, CCNE1, CDK2, CDK4, CIAPIN1
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| The study on expression of CIAPIN1 interfering hepatocellular carcinoma cell proliferation and its mechanisms.
|
| Huang Z, Su GF, Hu WJ, Bi XX, Zhang L, Wan G.
|
| Eur Rev Med Pharmacol Sci 21(13):3054-3060.
2017
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| 5 | CCNE1, CDK2, HOXA7
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| HOXA7 stimulates human hepatocellular carcinoma proliferation through cyclin E1/CDK2.
|
| Li Y, Yang XH, Fang SJ, Qin CF, Sun RL, Liu ZY, Jiang BY, Wu X, Li G.
|
| Oncol Rep 33(2):990-6. doi: 10.3892/or.2014.3668. Epub 2014 Dec 11.
2015
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| 6 | CDK2, KLF10, SIAH1
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| CDK2 phosphorylation regulates the protein stability of KLF10 by interfering with binding of the E3 ligase SIAH1.
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| Lin CH, Lin SY, Chang HW, Ko LJ, Tseng YS, Chang VH, Yu WC.
|
| Biochim Biophys Acta 1853(5):1174-81. doi: 10.1016/j.bbamcr.2015.02.018. Epub 2015 Feb 26.
2015
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| 7 | CCNA2, CDK2, PLA2G4A, SIRT2
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| Group IVA Cytosolic Phospholipase A2 Regulates the G2-to-M Transition by Modulating the Activity of Tumor Suppressor SIRT2.
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| Movahedi Naini S, Sheridan AM, Force T, Shah JV, Bonventre JV.
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| Mol Cell Biol 35(21):3768-84. doi: 10.1128/MCB.00184-15. Epub 2015 Aug 24.
2015
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| 8 | CDK2, RNF4
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| CDK-mediated RNF4 phosphorylation regulates homologous recombination in S-phase.
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| Luo K, Deng M, Li Y, Wu C, Xu Z, Yuan J, Lou Z.
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| Nucleic Acids Res 43(11):5465-75. doi: 10.1093/nar/gkv434. Epub 2015 May 6.
2015
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| 9 | CCP110, CDK2
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| CDK2 Inhibition Causes Anaphase Catastrophe in Lung Cancer through the Centrosomal Protein CP110.
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| Hu S, Danilov AV, Godek K, Orr B, Tafe LJ, Rodriguez-Canales J, Behrens C, Mino B, Moran CA, Memoli VA, Mustachio LM, Galimberti F, Ravi S, DeCastro A, Lu Y, Sekula D, Andrew AS, Wistuba II, Freemantle S, Compton DA, Dmitrovsky E.
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| Cancer Res 75(10):2029-38. doi: 10.1158/0008-5472.CAN-14-1494. Epub 2015 Mar 25.
2015
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| 10 | CCNA2, CDK2, CIZ1
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| Cyclin-A-CDK2-mediated phosphorylation of CIZ1 blocks replisome formation and initiation of mammalian DNA replication.
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| Copeland NA, Sercombe HE, Wilson RH, Coverley D.
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| J Cell Sci 128(8):1518-27. doi: 10.1242/jcs.161919. Epub 2015 Mar 3.
2015
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| 11 | CDK2, MYBBP1A, TPP2
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| TPPII, MYBBP1A and CDK2 form a protein-protein interaction network.
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| Nahálková J, Tomkinson B.
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| Arch Biochem Biophys 564:128-35. doi: 10.1016/j.abb.2014.09.017. Epub 2014 Oct 7.
2014
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| 12 | CDC6, CDK2, CUL4B, MCM2
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| CUL4B promotes replication licensing by up-regulating the CDK2-CDC6 cascade.
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| Zou Y, Mi J, Wang W, Lu J, Zhao W, Liu Z, Hu H, Yang Y, Gao X, Jiang B, Shao C, Gong Y.
|
| J Cell Biol 200(6):743-56. doi: 10.1083/jcb.201206065. Epub 2013 Mar 11.
2013
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| 13 | CDC25B, CDK2, CETN2
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| CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci.
|
| Boutros R, Mondesert O, Lorenzo C, Astuti P, McArthur G, Chircop M, Ducommun B, Gabrielli B.
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| PLoS One 8(7):e67822. doi: 10.1371/journal.pone.0067822. Print 2013.
2013
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| 14 | CDK2, FOXP3
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| Foxp3 protein stability is regulated by cyclin-dependent kinase 2.
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| Morawski PA, Mehra P, Chen C, Bhatti T, Wells AD.
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| J Biol Chem 288(34):24494-502. doi: 10.1074/jbc.M113.467704. Epub 2013 Jul 12.
2013
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| 15 | CCNA2, CDK1, CDK2
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| Cyclin-dependent kinase 1 (Cdk1) is essential for cell division and suppression of DNA re-replication but not for liver regeneration.
|
| Diril MK, Ratnacaram CK, Padmakumar VC, Du T, Wasser M, Coppola V, Tessarollo L, Kaldis P.
|
| Proc Natl Acad Sci U S A 109(10):3826-31. doi: 10.1073/pnas.1115201109. Epub 2012 Feb 21.
2012
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| 16 | CDK2, CDK2AP1, CDK2AP2, IKBKE
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| Human cyclin-dependent kinase 2-associated protein 1 (CDK2AP1) is dimeric in its disulfide-reduced state, with natively disordered N-terminal region.
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| Ertekin A, Aramini JM, Rossi P, Leonard PG, Janjua H, Xiao R, Maglaqui M, Lee HW, Prestegard JH, Montelione GT.
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| J Biol Chem 287(20):16541-9. doi: 10.1074/jbc.M112.343863. Epub 2012 Mar 14.
2012
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| 17 | CDK2
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| Cdk2 loss accelerates precursor differentiation and remyelination in the adult central nervous system.
|
| Caillava C, Vandenbosch R, Jablonska B, Deboux C, Spigoni G, Gallo V, Malgrange B, Baron-Van Evercooren A.
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| J Cell Biol. 193(2):397-407. 2011
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| 18 | CDK2
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| Mitotic progression becomes irreversible in prometaphase and collapses when Wee1 and Cdc25 are inhibited.
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| Potapova TA, Sivakumar S, Flynn JN, Li R, Gorbsky GJ.
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| Mol Biol Cell. 22(8):1191-206. 2011
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| 19 | CDH1, CDK2, USP37
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| Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.
|
| Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM.
|
| Mol Cell 42(4):511-23.
2011
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| 20 | CDK1, CDK2, CDK5, DNMT1
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| Phosphorylation of human DNMT1: implication of cyclin-dependent kinases.
|
| Lavoie G, St-Pierre Y.
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| Biochem Biophys Res Commun 409(2):187-92. Epub 2011 May 1.
2011
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| 21 | CDC6, CDK2, TREX1
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| Cdk2 is required for p53-independent G2/M checkpoint control.
|
| Chung JH, Bunz F.
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| PLoS Genet 6(2):e1000863. 2010
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| 22 | CDK1, CDK2, EZH2
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| Cyclin-dependent kinases regulate epigenetic gene silencing through phosphorylation of EZH2.
|
| Chen S, Bohrer LR, Rai AN, Pan Y, Gan L, Zhou X, Bagchi A, Simon JA, Huang H.
|
| Nat Cell Biol 2010 Oct 10. [Epub ahead of print]PMID: 20935635 2010
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| 23 | CDK1, CDK2
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| Nuclear pore formation but not nuclear growth is governed by cyclin-dependent kinases (Cdks) during interphase.
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| Maeshima K, Iino H, Hihara S, Funakoshi T, Watanabe A, Nishimura M, Nakatomi R, Yahata K, Imamoto F, Hashikawa T, Yokota H, Imamoto N.
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| Nat Struct Mol Biol 17(9):1065-71. Epub 2010 Aug 15.PMID: 20711190 2010
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| 24 | CDK2, CDK4, NPM2
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| Cdk2 and Cdk4 regulate the centrosome cycle and are critical mediators of centrosome amplification in p53-null cells.
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| Adon AM, Zeng X, Harrison MK, Sannem S, Kiyokawa H, Kaldis P, Saavedra HI.
|
| Mol Cell Biol 30(3):694-710. doi: 10.1128/MCB.00253-09. Epub 2009 Nov 23.
2010
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| 25 | CDK2
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| Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells.
|
| Neganova I, Zhang X, Atkinson S, Lako M.
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| Oncogene 28(1):20-30. Epub 2008 Sep 22.
2009
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| 26 | ANKRD17, CDK2
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| Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17.
|
| Deng M, Li F, Ballif BA, Li S, Chen X, Guo L, Ye X.
|
| J Biol Chem 284(12):7875-88. Epub 2009 Jan 16.
2009
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| 27 | CCNE1, CDK2, HINFP, NPAT
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| The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles.
|
| Xie R, Medina R, Zhang Y, Hussain S, Colby J, Ghule P, Sundararajan S, Keeler M, Liu LJ, van der Deen M, Mitra P, Lian JB, Rivera-Perez JA, Jones SN, Stein JL, van Wijnen AJ, Stein GS.
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| Proc Natl Acad Sci U S A 106(30):12359-64. Epub 2009 Jul 9.
2009
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| 28 | CDK2, KAT2B
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| The transcriptional co-activator PCAF regulates cdk2 activity.
|
| Mateo F, Vidal-Laliena M, Canela N, Zecchin A, Martínez-Balbás M, Agell N, Giacca M, Pujol MJ, Bachs O.
|
| Nucleic Acids Res 37(21):7072-84. doi: 10.1093/nar/gkp777. Epub .
2009
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| 29 | CCNE2, CDK2
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| Estrogen regulation of cyclin E2 requires cyclin D1 but not c-Myc.
|
| Caldon CE, Sergio CM, Schütte J, Boersma MN, Sutherland RL, Carroll JS, Musgrove EA.
|
| Mol Cell Biol 29(17):4623-39. doi: 10.1128/MCB.00269-09. Epub 2009 Jun 29.
2009
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| 30 | CDK2
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| Evidence of key role of Cdk2 overexpression in pemphigus vulgaris.
|
| Lanza A, Cirillo N, Rossiello R, Rienzo M, Cutillo L, Casamassimi A, de Nigris F, Schiano C, Rossiello L, Femiano F, Gombos F, Napoli C.
|
| J Biol Chem 283(13):8736-45. Epub 2008 Jan 16. 2008
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| 31 | CCNA1, CDK1, CDK2
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| Cyclin A/cdk2 coordinates centrosomal and nuclear mitotic events.
|
| De Boer L, Oakes V, Beamish H, Giles N, Stevens F, Somodevilla-Torres M, Desouza C, Gabrielli B.
|
| Oncogene 27(31):4261-8. Epub 2008 Mar 31.
2008
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| 32 | CDK2
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| Autocatalytic phosphorylation of CDK2 at the activating Thr160.
|
| Abbas T, Jha S, Sherman NE, Dutta A.
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| Cell Cycle 6(7):843-52. Epub 2007 Apr 13. 2007
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| 33 | CDK2
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| CDK2 is dispensable for adult hippocampal neurogenesis.
|
| Vandenbosch R, Borgs L, Beukelaers P, Foidart A, Nguyen L, Moonen G, Berthet C, Kaldis P, Gallo V, Belachew S, Malgrange B.
|
| Cell Cycle 6(24):3065-9. Epub 2007 Sep 14.PMID: 18073538 2007
|
| 34 | ATRIP, CDK2
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| Cyclin-dependent kinase 2 dependent phosphorylation of ATRIP regulates the G2-M checkpoint response to DNA damage.
|
| Myers JS, Zhao R, Xu X, Ham AJ, Cortez D.
|
| Cancer Res 67(14):6685-90.
2007
|
| 35 | CDK2
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| CDK2-dependent phosphorylation of FOXO1 as an apoptotic response to DNA damage.
|
| Huang H, Regan KM, Lou Z, Chen J, Tindall DJ.
|
| Science 314(5797):294-7. 2006
|
| 36 | CDK2
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| Membrane depolarization stimulates the proliferation of SH-SY5Y human neuroblastoma cells by increasing retinoblastoma protein (RB) phosphorylation through the activation of cyclin-dependent kinase 2 (Cdk2).
|
| Seo M, Kim Y, Lee YI, Kim SY, Ahn YM, Kang UG, Roh MS, Kim YS, Juhnn YS.
|
| Neurosci Lett 404(1-2):87-92. Epub 2006 Jul 7. 2006
|
| 37 | CDK2
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| Phosphorylation of the linker histone H1 by CDK regulates its binding to HP1alpha.
|
| Hale TK, Contreras A, Morrison AJ, Herrera RE.
|
| Mol Cell 22(5):693-9. 2006
|
| 38 | CDK2
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| Phosphorylation of RIalpha by cyclin-dependent kinase CDK 2/cyclin E modulates the dissociation of the RIalpha-RFC40 complex.
|
| Gupte RS, Traganos F, Darzynkiewicz Z, Lee MY.
|
| Cell Cycle 5(6):653-60. Epub 2006 Mar 15. 2006
|
| 39 | CDK2, CDKN1A
|
| Increased p21 expression and complex formation with cyclin E/CDK2 in retinoid-induced pre-B lymphoma cell apoptosis.
|
| Bao GC, Wang JG, Jong A.
|
| FEBS Lett 580(15):3687-93. Epub 2006 Jun 2. 2006
|
| 40 | CDK2
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| Human CDK2 inhibition modifies the dynamics of chromatin-bound minichromosome maintenance complex and replication protein A.
|
| Zhu Y, Ishimi Y, Tanudji M, Lees E.
|
| Cell Cycle 4(9):1254-63. Epub 2005 Sep 26. 2005
|
| 41 | CDK2
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| Cdk2-dependent Inhibition of p21 stability via a C-terminal cyclin-binding motif.
|
| Zhu H, Nie L, Maki CG.
|
| J Biol Chem 280(32):29282-8. Epub 2005 Jun 17. 2005
|
| 42 | CDK2
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| Acute reduction of an origin recognition complex (ORC) subunit in human cells reveals a requirement of ORC for Cdk2 activation.
|
| Machida YJ, Teer JK, Dutta A.
|
| J Biol Chem 280(30):27624-30. Epub 2005 Jun 7. 2005
|
| 43 | CDK2
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| CDK2 translational down-regulation during endothelial senescence.
|
| Freedman DA, Folkman J.
|
| Exp Cell Res 307(1):118-30. Epub 2005 Apr 21. 2005
|
| 44 | CDK2
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| Down-regulation of BRCA1-BARD1 ubiquitin ligase by CDK2.
|
| Hayami R, Sato K, Wu W, Nishikawa T, Hiroi J, Ohtani-Kaneko R, Fukuda M, Ohta T.
|
| Cancer Res 65(1):6-10. 2005
|
| 45 | CDK2
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| Cyclin-dependent kinase activity is required for progesterone receptor function: novel role for cyclin A/Cdk2 as a progesterone receptor coactivator.
|
| Narayanan R, Adigun AA, Edwards DP, Weigel NL.
|
| Mol Cell Biol 25(1):264-77. 2005
|
| 46 | CDK2, PURA
|
| Functional interaction of Puralpha with the Cdk2 moiety of cyclin A/Cdk2.
|
| Liu H, Barr SM, Chu C, Kohtz DS, Kinoshita Y, Johnson EM.
|
| Biochem Biophys Res Commun 328(4):851-7.
2005
|
| 47 | CDK2, HSP90AA1
|
| Proteomic analysis of human O6-methylguanine-DNA methyltransferase by affinity chromatography and tandem mass spectrometry.
|
| Niture SK, Doneanu CE, Velu CS, Bailey NI, Srivenugopal KS.
|
| Biochem Biophys Res Commun. 337(4):1176-84. 2005
|
| 48 | CDK2, UHRF2
|
| NIRF induces G1 arrest and associates with Cdk2.
|
| Li Y, Mori T, Hata H, Homma Y, Kochi H.
|
| Biochem Biophys Res Commun 319(2):464-8. 2004
|
| 49 | CDK2
|
| Critical role of CDK2 for melanoma growth linked to its melanocyte-specific transcriptional regulation by MITF.
|
| Du J, Widlund HR, Horstmann MA, Ramaswamy S, Ross K, Huber WE, Nishimura EK, Golub TR, Fisher DE.
|
| Cancer Cell 6(6):565-76. 2004
|
| 50 | CCNA1, CDK2, INCA1, KLHDC9, PROCA1
|
| Identification of interaction partners and substrates of the cyclin A1-CDK2 complex.
|
| Diederichs S, Bäumer N, Ji P, Metzelder SK, Idos GE, Cauvet T, Wang W, Möller M, Pierschalski S, Gromoll J, Schrader MG, Koeffler HP, Berdel WE, Serve H, Müller-Tidow C.
|
| J Biol Chem 279(32):33727-41. Epub 2004 May 24. 2004
|
| 51 | CDK2
|
| Cyclin-dependent kinases regulate the antiproliferative function of Smads.
|
| Matsuura I, Denissova NG, Wang G, He D, Long J, Liu F.
|
| Nature. 430(6996):226-31. 2004
|
| 52 | CDK2
|
| p42, a novel cyclin-dependent kinase-activating kinase in mammalian cells.
|
| Liu Y, Wu C, Galaktionov K.
|
| J Biol Chem. 279(6):4507-14. 2004
|
| 53 | IRF1, CDK2
|
| The tumor suppressor interferon regulatory factor 1 interferes with SP1 activation to repress the human CDK2 promoter.
|
| Xie RL, Gupta S, Miele A, Shiffman D, Stein JL, Stein GS, van Wijnen AJ.
|
| J Biol Chem 278(29):26589-96. Epub 2003 May 5. 2003
|
| 54 | CDK2
|
| Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice.
|
| Ortega S, Prieto I, Odajima J, Martín A, Dubus P, Sotillo R, Barbero JL, Malumbres M, Barbacid M.
|
| Nat Genet. 35(1):25-31 2003
|
| 55 | CDK2, SPDYA
|
| Human Speedy: a novel cell cycle regulator that enhances proliferation through activation of Cdk2.
|
| Porter LA, Dellinger RW, Tynan JA, Barnes EA, Kong M, Lenormand JL, Donoghue DJ.
|
| J Cell Biol 157(3):357-66. Epub 2002 Apr 29. 2002
|
| 56 | CDK2
|
| Characterization and expression of mammalian cyclin b3, a prepachytene meiotic cyclin.
|
| Nguyen TB, Manova K, Capodieci P, Lindon C, Bottega S, Wang XY, Refik-Rogers J, Pines J, Wolgemuth DJ, Koff A.
|
| J Biol Chem. 277(44):41960-9. 2002
|
| 57 | CDK2
|
| Reciprocal activation by cyclin-dependent kinases 2 and 7 is directed by substrate specificity determinants outside the T loop.
|
| Garrett S, Barton WA, Knights R, Jin P, Morgan DO, Fisher RP.
|
| Mol Cell Biol. 21(1):88-99. 2001
|
| 58 | CDK2
|
| Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
|
| Song H, Hanlon N, Brown NR, Noble ME, Johnson LN, Barford D.
|
| Mol Cell. 7(3):615-26. 2001
|
| 59 | CDK2
|
| HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression.
|
| Hall C, Nelson DM, Ye X, Baker K, DeCaprio JA, Seeholzer S, Lipinski M, Adams PD.
|
| Mol Cell Biol. 21(5):1854-65. 2001
|
| 60 | CDK2
|
| C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4.
|
| Wang H, Iakova P, Wilde M, Welm A, Goode T, Roesler WJ, Timchenko NA.
|
| Mol Cell. 8(4):817-28. 2001
|
| 61 | CDK2
|
| Cyclin A1 directly interacts with B-myb and cyclin A1/cdk2 phosphorylate B-myb at functionally important serine and threonine residues: tissue-specific regulation of B-myb function.
|
| Müller-Tidow C, Wang W, Idos GE, Diederichs S, Yang R, Readhead C, Berdel WE, Serve H, Saville M, Watson R, Koeffler HP.
|
| Blood. 97(7):2091-7. 2001
|
| 62 | CDK2, CDKN3
|
| Phosphoprotein-protein interactions revealed by the crystal structure of kinase-associated phosphatase in complex with phosphoCDK2.
|
| Song H, Hanlon N, Brown NR, Noble ME, Johnson LN, Barford D.
|
| Mol Cell 7(3):615-26.
2001
|
| 63 | CCNE1, CDK2, NPM1
|
| Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication.
|
| Okuda M, Horn HF, Tarapore P, Tokuyama Y, Smulian AG, Chan PK, Knudsen ES, Hofmann IA, Snyder JD, Bove KE, Fukasawa K.
|
| Cell 103(1):127-40. 2000
|
| 64 | CDK2
|
| p12(DOC-1) is a novel cyclin-dependent kinase 2-associated protein.
|
| Shintani S, Ohyama H, Zhang X, McBride J, Matsuo K, Tsuji T, Hu MG, Hu G, Kohno Y, Lerman M, Todd R, Wong DT.
|
| Mol Cell Biol. 20(17):6300-7. 2000
|
| 65 | CDK2
|
| A direct interaction between proliferating cell nuclear antigen (PCNA) and Cdk2 targets PCNA-interacting proteins for phosphorylation.
|
| Koundrioukoff S, Jónsson ZO, Hasan S, de Jong RN, van der Vliet PC, Hottiger MO, Hübscher U.
|
| J Biol Chem. 275(30):22882-7. 2000
|
| 66 | CDK2
|
| PKCeta associates with cyclin E/cdk2/p21 complex, phosphorylates p21 and inhibits cdk2 kinase in keratinocytes.
|
| Kashiwagi M, Ohba M, Watanabe H, Ishino K, Kasahara K, Sanai Y, Taya Y, Kuroki T.
|
| Oncogene. 19(54):6334-41. 2000
|
| 67 | CDK2
|
| Stress-induced activation of protein kinase CK2 by direct interaction with p38 mitogen-activated protein kinase.
|
| Sayed M, Kim SO, Salh BS, Issinger OG, Pelech SL.
|
| J Biol Chem 275(22):16569-73 2000
|
| 68 | CDK2
|
| TOK-1, a novel p21Cip1-binding protein that cooperatively enhances p21-dependent inhibitory activity toward CDK2 kinase.
|
| Ono T, Kitaura H, Ugai H, Murata T, Yokoyama KK, Iguchi-Ariga SM, Ariga H.
|
| J Biol Chem. 275(40):31145-54. 2000
|
| 69 | CDK2, CCNE1
|
| Deregulated cyclin E induces chromosome instability.
|
| Spruck CH, et al.
|
| Nature 401(6750):297-300 1999
|
| 70 | CCNA2, CDK2, SKP2
|
| Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2.
|
| Yam CH, Ng RW, Siu WY, Lau AW, Poon RY.
|
| Mol Cell Biol 19(1):635-45.
1999
|
| 71 | CDK2
|
| Cyclin E2, a novel G1 cyclin that binds Cdk2 and is aberrantly expressed in human cancers.
|
| Gudas JM, Payton M, Thukral S, Chen E, Bass M, Robinson MO, Coats S.
|
| Mol Cell Biol. 19(1):612-22. 1999
|
| 72 | CDK2
|
| Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.
|
| Petersen BO, Lukas J, Sřrensen CS, Bartek J, Helin K.
|
| EMBO J. 18(2):396-410. 1999
|
| 73 | CDK2
|
| Regulation of cyclin A-Cdk2 by SCF component Skp1 and F-box protein Skp2.
|
| Yam CH, Ng RW, Siu WY, Lau AW, Poon RY.
|
| Mol Cell Biol. 19(1):635-45. 1999
|
| 74 | CDK2
|
| Regulation of cell growth-dependent expression of mammalian CDC6 gene by the cell cycle transcription factor E2F.
|
| Ohtani K, Tsujimoto A, Ikeda M, Nakamura M.
|
| Oncogene 17 : 1777-1785. 1998
|
| 75 | BAX, BCL2, CDK2
|
| A link between cell cycle and cell death : Bax and Bcl-2 modulate Cdk2 activation during thymocyte apoptosis.
|
| Gil-Gomez G, Berns A, Brady HJ.
|
| EMBO J 17 : 7209-7218. 1998
|
| 76 | CDK2
|
| Interferon-induces expression of cyclin-dependent kinase-inhibitors p21WAF1 and p27Kip1 that prevent activation of cyclin-dependent kinase by CDK-activating kinase (CAK).
|
| Mandal M, Bandyopadhyay D, Goepfert TM, Kumar R.
|
| Oncogene. 16(2):217-25. 1998
|
| 77 | CDK2
|
| Characterization of the p125 subunit of human DNA polymerase delta and its deletion mutants. Interaction with cyclin-dependent kinase-cyclins.
|
| Wu SM, Zhang P, Zeng XR, Zhang SJ, Mo J, Li BQ, Lee MY.
|
| J Biol Chem. 273(16):9561-9. 1998
|
| 78 | CDK2
|
| Association of Cdk2/cyclin E and NF-kappa B complexes at G1/S phase.
|
| Chen E, Li CC.
|
| Biochem Biophys Res Commun. 249(3):728-34. 1998
|
| 79 | CDK2
|
| BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases.
|
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