Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | C6 | contributors: - updated : 15-01-2007 |
HGNC name | complement component 6 |
HGNC id | 1339 |
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Corresponding disease |
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Location | 5p13 Physical location : 41.142.335 - 41.261.540 | ||
Synonym name | complement component 6, beta-2 globulin 5.2S |
DNA |
TYPE | functioning gene |
SPECIAL FEATURE | opposite orientation, tail to tail |
text | tail to tail with C7 |
STRUCTURE | 71.00 kb 18 Exon(s) |
10 Kb 5' upstream gene genomic sequence study |
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MAPPING | cloned | Y | linked | Y | status | confirmed |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | restricted |
constitutive of |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
conjugated | GlycoP |
isoforms | Precursor |
HOMOLOGY |
interspecies | ortholog to murine C6 |
ortholog to rattus c6 | |
ortholog to chimpanzee c6 |
Homologene |
FAMILY | complement C6/C7/C8/C9 family |
CATEGORY | immunity/defense , secretory |
SUBCELLULAR LOCALIZATION | extracellular |
plasma membrane | |
text |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS | immunity/defense |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | C6 |
related resource | C6base - Mutation registry for C6 deficiency |
Susceptibility |
Variant & Polymorphism
| |
Candidate gene
Marker
| Therapy target
|
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ANIMAL & CELL MODELS |