Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | ATXN10 | contributors: mct - updated : 15-05-2013 |
HGNC name | ataxin 10 |
HGNC id | 10549 |
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Corresponding disease |
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Location | 22q13.31 Physical location : 46.067.677 - 46.241.186 | ||||
Synonym name | |||||
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Synonym symbol(s) | E46L, ATXX, FLJ37990 |
DNA |
TYPE | functioning gene |
STRUCTURE | 173.14 kb 12 Exon(s) |
motif | repetitive sequence triplet |
MAPPING | cloned | Y | linked | N | status | provisional |
RNA |
TRANSCRIPTS | type | messenger |
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EXPRESSION |
Type | ubiquitous |
expressed in | (based on citations) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
organ(s) |
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cell lineage
cell lines
| fluid/secretion
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at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
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motifs/domains
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conjugated | ubiquitinated |
HOMOLOGY |
interspecies | homolog to murine Sca10 |
Homologene |
FAMILY | |
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CATEGORY | regulatory |
SUBCELLULAR LOCALIZATION | intracellular |
intracellular,cytoplasm,cytosolic | |
intracellular,nuclear envelope |
basic FUNCTION | |
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CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism |
signaling |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
cell & other |
REGULATION |
Phosphorylated by | PLK1 (PLK1 phosphorylation of Ataxin-10 influences its degradation and cytokinesis, which may provide mechanistic insight to SCA10 pathogenesis) |
ASSOCIATED DISORDERS |
corresponding disease(s) | SCA10 , NPHP17 |
Susceptibility |
Variant & Polymorphism
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Candidate gene
Marker
| Therapy target
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ANIMAL & CELL MODELS |