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FLASH GENE

Symbol

IRF7

contributors: mct/ - updated : 30-01-2018

HGNC name	interferon regulatory factor 7
HGNC id	6122

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

Irf7-null mice are consistently more vulnerable than Myd88-null mice to viral infection, and this correlated with marked decrease in serum interferon levels, indicating the importance of the IRF7-dependent induction of systemic interferon responses for innate antiviral immunity