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FLASH GENE

Symbol

S100A1

contributors: mct - updated : 10-02-2018

HGNC name	S100 calcium binding protein A1
HGNC id	10486

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	ATP synthase activity is reduced in cardiomyocytes from S100a1 knockout mice
	mice deficient of both the S100a1 and S100b genes displayed normal skeletal growth from embryonic stage to adulthood
	S100a1-knock-out mice (KO) exhibited increased right ventricular (RV) weight/body weight ratio and elevated RV pressure in the absence of altered left ventricular filling pressures, accompanied by increase in wall thickness of muscularized pulmonary arteries and a reduction in microvascular perfusion