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Symbol S100A1 contributors: mct - updated : 10-02-2018
HGNC name S100 calcium binding protein A1
HGNC id 10486
  • ATP synthase activity is reduced in cardiomyocytes from S100a1 knockout mice
  • mice deficient of both the S100a1 and S100b genes displayed normal skeletal growth from embryonic stage to adulthood
  • S100a1-knock-out mice (KO) exhibited increased right ventricular (RV) weight/body weight ratio and elevated RV pressure in the absence of altered left ventricular filling pressures, accompanied by increase in wall thickness of muscularized pulmonary arteries and a reduction in microvascular perfusion