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FLASH GENE
Symbol DDB2 contributors: mct - updated : 04-12-2017
HGNC name damage-specific DNA binding protein 2, 48kDa
HGNC id 2718
ANIMAL & CELL MODELS
  • DDB2/ mice are susceptible to UV-induced skin carcinogenesis
  • mice genetically deficient in Ddb2 exhibited increased susceptibility to colon tumor development in a manner associated with higher abundance of the Wnt receptor-expressing cells and greater activation of the downstream Wnt pathway