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FLASH GENE

Symbol

TEAD1

contributors: mct - updated : 06-03-2019

HGNC name	TEA domain family member 1 (SV40 transcriptional enhancer factor)
HGNC id	11714

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ANIMAL & CELL MODELS

	transgenic mice overexpressing TEAD1 showed an age-dependent heart dysfunction
	homozygous mutant mice embryos with a targeted disruption of the TEAD1 gene displayed abnormal heart development and died between embryonic days 11 and 12
	murine Tead1-deficient cardiomyocytes have significantly decreased proliferation during the immediate postnatal period, when proliferation rate is normally high