Symbol
| CD84
| contributors: mct - updated : 16-02-2016
|
HGNC name
| CD84 molecule
|
HGNC id
| 1704
|
Other morbid association(s)
|
Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --over
|  
|
in Kawasaki disease (KD)coronary arteries in patients with acute and chronic arterial disease | tumoral
|  
|  
| --over
|  
|
in CLL is an important survival mechanism that appears to be an early event in the pathogenesis of the disease | |
Variant & Polymorphism
|
| |
Candidate gene
Marker
Therapy target
|
System | Type | Disorder | Pubmed |
cancer | hemopathy | | |
therapeutic strategies based on the blockade of the CD84-dependent survival pathway in Chronic lymphocytic leukemia (CLL) |
| | | |
| Cd84(-/-) mice exhibited unaltered hemostatic function and arterial thrombus formation |