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FLASH GENE

Symbol

JAG2

contributors: mct/pgu - updated : 19-05-2021

HGNC name	jagged 2
HGNC id	6189

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

LGMDR27

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in malignant plasma cells from multiple myeloma constitutional     --over   significantly increased in the colorectal cancer cell lines compared with that of normal colorectal cell line

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	high JAG2 expression may be useful as additional marker to identify aggressive Medulloblastoma (MB)
Therapy target
	System Type Disorder Pubmed cancer digestive colon therapeutic target for the treatment of colorectal cancer

ANIMAL & CELL MODELS