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FLASH GENE
Symbol MAX contributors: mct - updated : 13-03-2024
HGNC name MYC associated factor X
HGNC id 6913
ASSOCIATED DISORDERS
corresponding disease(s) GDDMP
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral germinal mutation      
in hereditary pheochromocytoma, with metastatic potential
tumoral     --over  
significantly increased expression of MAX protein in growth hormone-secreting pituitary adenoma (GHPA) compared to nonfunctional pituitary adenoma (NFPA)
constitutional     --low  
significantly downregulated in the stromal cells derived from decidual tissues of women with recurrent spontaneous abortion (RSA)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS