Symbol
| LTBR
| contributors: SGE/npt - updated : 31-05-2010
|
HGNC name
| lymphotoxin beta receptor (TNFR superfamily, member 3)
|
HGNC id
| 6718
|
Variant & Polymorphism
|
| |
Candidate gene
| constitutively inducing NF-KappaB activation and it may be associated with autonomous growth of melanoma cells (Dhawan 2008) |
Marker
Therapy target
| | |
| engagment of Ltbr by Tnfsf14 is essential for both intestinal inflammation and hyperserum IgA syndrome in a murine model that spontaneously develops T cell-mediated intestinal inflammation (Wang 2004) |