| Other morbid association(s)
|
| Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
|---|
| tumoral
|
| deletion
|
|
| |
212delC associated with familial acute myeloblastic leukemia with good prognostic | | tumoral
|
|
|
| loss of function
| |
or low expressed in acute myeloid leukemia | | tumoral
| somatic mutation
|
|
|
|
cause a myeloid differentiation block and were detected in acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), multiple myeloma and non-Hodgkin's lymphoma (NHL)  | | tumoral
|
|
| --low
|
| |
contributes to MN1-modulated proliferation and impaired myeloid differentiation of hematopoietic cells | | tumoral
|
|
|
| loss of function
| |
SOX4 overexpression resulting from its inactivation contributes to the development of leukemia with a distinct leukemia-initiating cells (LICs) phenotype | |
