Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

IL17A

contributors: mct/shn - updated : 02-03-2016

HGNC name	interleukin 17A
HGNC id	5981

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in the invasive group of pituitary adenomas (pMID: 21279695)

Susceptibility

to rheumatoid arthritis

Variant & Polymorphism

Candidate gene
Marker	novel indicator of prognosis in the patients with colorectal carcinoma
Therapy target
	System Type Disorder Pubmed cancer digestive colon could serve as a novel therapeutic target for colorectal carcinoma cancer digestive colon IL17A and IL17RA are therapeutic targets in colorectal cancer

ANIMAL & CELL MODELS

	IL-17-deficient mice display contact, delayed-type, and airway hypersensitivity responses, and reduced T-dependent antibody production
	IL-17-deficient mice exhibit a markedly suppressed collagen-induced arthritis
	Mice deficient in IL-17A demonstrated delayed healing and decreased IL-17A production after skin infection with C. albicans