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FLASH GENE
Symbol CPA1 contributors: mct - updated : 02-05-2014
HGNC name carboxypeptidase A1 (pancreatic)
HGNC id 2296
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility to nonalcoholic chronic pancreatitis
Variant & Polymorphism other
  • loss-of-function CPA1 variants are strongly associated with nonalcoholic chronic pancreatitis, especially early onset disease (PMId:23955596)
  • Candidate gene
    Marker
  • increased pro-CPA1 and CPA1 levels is a biomarker for the diagnosis of pancreatitis and pancreatic cancer
  • Therapy target
    ANIMAL & CELL MODELS