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FLASH GENE
Symbol UQCRB contributors: mct - updated : 24-11-2020
HGNC name ubiquinol-cytochrome c reductase binding protein
HGNC id 12582
ASSOCIATED DISORDERS
corresponding disease(s) CMP3D
related resource MITOP database
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral       loss of function
inhibits the cancer stem cell-like properties in glioblastoma cells
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerbrainglioma/neuroblstoma
UQCRB and its inhibitors could be a new therapeutic target and lead compounds for eliminating cancer stem cells in glioblastoma
cancerangiogenesis 
mitochondrial UQCRB modulators are promising antiangiogenic agents
ANIMAL & CELL MODELS