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FLASH GENE
Symbol LTC4S contributors: KTN/npt - updated : 04/11/2008
HGNC name leukotriene C4 synthase
HGNC id 6719
ASSOCIATED DISORDERS
corresponding disease(s) LTC4SD
Susceptibility to asthma and aspirin-intolerant asthma
Variant & Polymorphism SNP
  • a -444A/C polymorphism creating an extra recognition site for AP2 enhancer
  • a -1072G/A substitution generating an additional LF-A1 and alpha-INF-2 site
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS