Selected-GenAtlas references | SOURCE | GeneCards | NCBI Gene | Swiss-Prot | Orphanet | Ensembl |
HGNC | UniGene | Nucleotide | OMIM | UCSC |
Home Page |
FLASH GENE |
Symbol | LTC4S | contributors: KTN/npt - updated : 04/11/2008 |
HGNC name | leukotriene C4 synthase |
HGNC id | 6719 |
|
EXPRESSION |
Type |
expressed in | (based on citations) | ||||||||||||||||||||
organ(s) |
|
tissue |
|
cells |
|
cell lineage
cell lines
| fluid/secretion
| |
at STAGE |
PROTEIN |
PHYSICAL PROPERTIES
STRUCTURE
| |
motifs/domains
| |
| |
|
conjugated | GlycoP |
mono polymer | homomer , dimer |
HOMOLOGY |
interspecies | homolog to dog LTC4S (91 pc) |
homolog to chimpanzee LTC4S (99.3 pc) | |
homolog to cow LTC4S (97 pc) | |
homolog to rattus Ltc4s (86 pc) | |
homolog to murine Ltc4s (88 pc) |
Homologene |
FAMILY |
CATEGORY | enzyme , regulatory |
basic FUNCTION | |
| |
|
CELLULAR PROCESS |
PHYSIOLOGICAL PROCESS |
PATHWAY |
metabolism | lipid/lipoprotein |
signaling |
leukotriene biosynthesis |
a component |
INTERACTION |
DNA |
RNA |
small molecule |
protein |
cell & other |
REGULATION |
ASSOCIATED DISORDERS |
corresponding disease(s) | LTC4SD |
Susceptibility | to asthma and aspirin-intolerant asthma |
Variant & Polymorphism SNP | |
| |
Candidate gene
Marker
| Therapy target
|
| |
ANIMAL & CELL MODELS |