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FLASH GENE

Symbol

PPP3CA

contributors: mct - updated : 18-05-2016

HGNC name	protein phosphatase 3, catalytic subunit, alpha isozyme
HGNC id	9314

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

IECEE

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in the diabetic kidney

Susceptibility

to cardiac hypertrophy

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

	transgenic mice overexpressing a truncated form of the murine calcineurin A-alpha catalytic subunit under the control of the CaMKII alpha promoter
	transgenic mice expressing the calcineurin inhibitory domains of either calcineurin-binding protein 1 or A kinase-anchoring protein 79