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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

HK2

contributors: mct/npt/pgu - updated : 22-12-2020

HGNC name	hexokinase 2
HGNC id	4923

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

related resource

MITOP database

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   HK2 overexpression correlates with worse overall survival of glioblastoma patients

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	HK2 status was an independent prognostic factor for both disease-free and overall survival in colorectal carcinoma
Therapy target
	System Type Disorder Pubmed cancer lung   promising treatment target for NSCLC with KRAS activating and TP53 function loss

ANIMAL & CELL MODELS