Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Orphanet	Ensembl
	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

XDH

contributors: mct - updated : 10-05-2017

HGNC name	xanthine dehydrogenase
HGNC id	12805

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

XDH1

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in liver disease (cirrhosis)

Susceptibility

to hypertension

Variant & Polymorphism other	XDH gene polymorphisms rs1042039, rs1054889, and rs2073316 may be associated with hypertension

Candidate gene
Marker	is a breast cancer biomarker
Therapy target
	System Type Disorder Pubmed diabete metabolic syndrom   XDH inhibitors may be useful for preventing atherosclerosis cancer reproductive breast target for pharmacologic activation in therapeutic management of aggressive breast cancer

ANIMAL & CELL MODELS