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FLASH GENE

Symbol

UBASH3B

contributors: mct - updated : 04-07-2018

HGNC name	ubiquitin associated and SH3 domain containing, B
HGNC id	29884

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in aggressive tumors

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     inhibition of UBASH3B may offer an attractive therapeutic perspective for cancers cancer reproductive breast potential therapeutic target for TNBC

ANIMAL & CELL MODELS

Ubash3a/Ubash3b-deficient mice show a profound expansion of multipotent progenitor and lymphoid primed multipotent progenitor cells with elevated colony-forming capacity