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	HGNC	UniGene	Nucleotide	OMIM		UCSC

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FLASH GENE

Symbol

GPSM2

contributors: mct - updated : 12-07-2015

HGNC name	G-protein signaling modulator 2
HGNC id	29501

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DFNB82 , CMCS

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in a large proportion of breast cancers

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer reproductive breast PBK/GPSM2 pathway might be a promising molecular target for treatment of breast cancer

ANIMAL & CELL MODELS

cortically polarized in mouse oocytes and is critical for meiotic spindle organization