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FLASH GENE

Symbol

MOAP1

contributors: mct - updated : 05-09-2018

HGNC name	modulator of apoptosis 1
HGNC id	16658

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   sensitizes cells to apoptotic stimuli and promotes recombinant BAX-mediated cytochrome c release from isolated mitochondria

Susceptibility

Variant & Polymorphism

Candidate gene

Marker

Therapy target

ANIMAL & CELL MODELS

Moap-1-deficient mice are resistant to Fas-induced hepatocellular apoptosis and lethality