Selected-GenAtlas references SOURCE GeneCards NCBI Gene Swiss-Prot Ensembl
HGNC UniGene Nucleotide OMIM UCSC
Home Page
FLASH GENE
Symbol PRICKLE2 contributors: mct/npt - updated : 17-02-2014
HGNC name prickle homolog 2 (Drosophila)
HGNC id 20340
ASSOCIATED DISORDERS
corresponding disease(s) EGI2
Susceptibility to Autism spectrum disorders (ASDs)
Variant & Polymorphism other
  • variants causing a critical loss of PRICKLE2 function, are associated with ASD
  • Candidate gene
    Marker
    Therapy target
    ANIMAL & CELL MODELS
  • mice with disruption in Prickle2 display behavioral abnormalities including altered social interaction, learning abnormalities and behavioral inflexibility