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FLASH GENE

Symbol

NCAPG2

contributors: mct - updated : 29-01-2019

HGNC name	non-SMC condensin II complex, subunit G2
HGNC id	21904

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

MRSRBD

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --over   in non-small cell lung cancer tissues compared to adjacent normal lung tissues, and significantly correlated with lymph node metastasis and pathologic-Tumour Nodes Metastasen stages

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	poor prognostic biomarker in lung adenocarcinoma
Therapy target
	System Type Disorder Pubmed cancer     simultaneous targeting of NCAPG2 and TRAPPC2 is a promising strategy for the development of antitumor drugs as a treatment for intractable tumours

ANIMAL & CELL MODELS

suppression and mutation of Ncapg2 results in apoptosis and altered mitotic progression in Zebrafish Larvae