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FLASH GENE
Symbol CPT1C contributors: mct/shn - updated : 09-12-2016
HGNC name carnitine palmitoyltransferase 1C
HGNC id 18540
ASSOCIATED DISORDERS
corresponding disease(s) SPG73
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • CPT1c KO mice have lower body weight and food intake, exhibit decreased rates of fatty acid oxidation and are more susceptible to obesity
  • double transgenic mice CPT1c-TgN displayed severe growth retardation and a greater reduction in brain weight in the postnatal period with a stunted development at 2 weeks of age