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FLASH GENE
Symbol RAD21L1 contributors: mct - updated : 29-09-2016
HGNC name RAD21-like 1 (S. pombe)
HGNC id 16271
ASSOCIATED DISORDERS
corresponding disease(s)
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
ANIMAL & CELL MODELS
  • male mice lacking Rad21l are defective in full synapsis of homologous chromosomes at meiotic prophase I, which provokes an arrest at zygotene and leads to total azoospermia and consequently infertility, however Rad21l-deficient females are fertile but develop an age-dependent sterility