Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

CREG1

contributors: mct - updated : 20-11-2019

HGNC name	cellular repressor of E1A-stimulated genes
HGNC id	2351

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   dramatically downregulated in atherosclerotic lesions

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular atheroma cardiac may be a useful therapeutic adjunct for transplanting MSCs into damaged heart after myocardial infarction cardiovascular aquired   autophagy activation via CREG1 may be a viable therapeutic strategy autophagy for improving cardiac performance under pathologic conditions

ANIMAL & CELL MODELS

	in mice, global deletion of the Creg1 gene leads to early embryonic death
	Creg1+/- mice exhibited a more prominent obesity phenotype with no change in food intake compared with WT controls when challenged with high fat diet (HFD)