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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

KCNA3

contributors: mct - updated : 09-02-2013

HGNC name	potassium voltage-gated channel, shaker-related subfamily, member 3
HGNC id	6221

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --over   in autoimmune diseases (type 1 diabetes mellitus, multiple sclerosis, rheumatoid arthritis)

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cardiovascular atheroma   selective targeting of KCNA3 in CD4(+)CD28null T cells may hold potential therapeutic promise for acute coronary syndrome immunology autoimmune   therapeutic target for T cell-mediated autoimmune diseases, by KCNA3 blockers

ANIMAL & CELL MODELS