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FLASH GENE
Symbol CARD10 contributors: mct/npt/pgu - updated : 16-04-2013
HGNC name caspase recruitment domain family, member 10
HGNC id 16422
ASSOCIATED DISORDERS
corresponding disease(s)
Other morbid association(s)
TypeGene ModificationChromosome rearrangementProtein expressionProtein Function
tumoral     --over  
in colon cancers and contributes to malignant cell growth by facilitating cell cycle progression through NFKB mediated upregulation of CCND1
Susceptibility
Variant & Polymorphism
Candidate gene
Marker
Therapy target
SystemTypeDisorderPubmed
cancerlung 
could serve as a potential companion drug target, along with NFKB and EGFR in EGFR-mutant lung cancers
ANIMAL & CELL MODELS