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	HGNC	UniGene	Nucleotide	OMIM	UCSC

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FLASH GENE

Symbol

PPP1R13B

contributors: mct - updated : 13-02-2008

HGNC name	protein phosphatase 1, regulatory (inhibitor) subunit 13B
HGNC id	14950

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --low   by hypermethylation of the 5'-untranslated region in cancer cell lines retaining wild-type TP53 tumoral     --low   frequently downregulated in in breast carcinomas expressing wild type TP53 (not with mutant TP53) tumoral       loss of function by aberrant methylation of its promoter in acute lymphoblastic leukemia

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed cancer     target for cancer therapy

ANIMAL & CELL MODELS