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FLASH GENE

Symbol

FABP7

contributors: mct - updated : 17-02-2017

HGNC name	fatty acid binding protein 7, brain
HGNC id	3562

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function constitutional     --low   in fetal CCAM (congenital cystic adenomatoid malformation) compared with fetal lung

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	can be used as a potential diagnostic biomarker of early-stage melanoma systemic spreading in blood
Therapy target

ANIMAL & CELL MODELS

	Fabp7-deficient mice and transgenic flies that express the FABP7.T61M missense mutation in astrocytes show fragmented sleep
	Fabp7-/- mice have significantly decreased retinal venular caliber retinal arteriolar fractal dimension compared with WT littermates