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FLASH GENE

Symbol

MYO1A

contributors: mct - updated : 28-08-2013

HGNC name	myosin IA
HGNC id	7595

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

DFNA48

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral       loss of function frequently inactivated in colorectal tumors by genetic and epigenetic mechanism

Susceptibility

Variant & Polymorphism

Candidate gene
Marker	MYO1A levels can be used to predict the probability of patient survival in colorectal cancer
Therapy target

ANIMAL & CELL MODELS

mice lacking Myo1a demonstrate no overt physiological symptoms, suggesting that other myosins may compensate for the loss of Myo1a in these animals