Selected-GenAtlas references	SOURCE	GeneCards	NCBI Gene	Swiss-Prot	Ensembl
	HGNC	UniGene	Nucleotide	OMIM	UCSC

Home Page

FLASH GENE

Symbol

CHRNA5

contributors: mct/npt - updated : 28-01-2020

HGNC name	cholinergic receptor, nicotinic, alpha 5
HGNC id	1959

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Susceptibility

to lung cancer to alcohol and nicotine use disorders to nicotine dependence and lung cancer (Spitz 2008) to chronic obstructive pulmonary disease (COPD)

Variant & Polymorphism SNP	rs8034191
	variants were associated with higher risks of lung cancer in lower smoking-exposed strata, and in individuals with a strong family history of lung or smoking-related cancers (Spitz 2008)

Candidate gene	for low penetrance, high-frequency lung cancer susceptiblity genes
Marker
Therapy target

ANIMAL & CELL MODELS