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FLASH GENE

Symbol

THRA

contributors: mct - updated : 03-06-2020

HGNC name	thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)
HGNC id	11796

FLASH GENE DNA RNA EXPRESSION PROTEIN DISORDER ANIMAL & CELL MODELS

ASSOCIATED DISORDERS

corresponding disease(s)

Other morbid association(s)

Type Gene Modification Chromosome rearrangement Protein expression Protein Function tumoral     --other   dysregulated in breast cancer

Susceptibility

Variant & Polymorphism

Candidate gene
Marker
Therapy target
	System Type Disorder Pubmed neurosensorial visual   inhibition of THRA, THRB locally in the retina is a therapeutic strategy for retinal degeneration

ANIMAL & CELL MODELS

thyroid receptor knock-out mouse models displaying severe neurological dysfunction