Type | Gene Modification | Chromosome rearrangement | Protein expression | Protein Function
|
---|
constitutional
|  
|  
| --low
|  
|
in cardiac heart failure and coronary heart disease |
constitutional
|  
|  
| --over
|  
|
during adipocyte differentiation stage |
constitutional
|  
|  
| --over
|  
|
in hepatic cirrhosis (Principe 2008) |
constitutional
|  
|  
| --other
|  
|
might be involved in the mechanism of establishment of overt diabetes mellitus as well as associated atherosclerotic complications (Erdem 2008) |
constitutional
|  
|  
| --over
|  
|
in aortic valve stenosis, of the apelin-APLNR signaling pathway (Peltonen 2009) |
constitutional
|  
|  
| --low
|  
|
in women with polycystic ovary syndrome |
constitutional
|  
|  
| --over
|  
|
of APLN or APLNR promoted the hypoxia-induced proliferation of the Endothelial progenitor cells (EPCs) |