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FLASH GENE
Symbol PDE1B contributors: mct/npt - updated : 30-06-2008
HGNC name phosphodiesterase 1B, calmodulin-dependent
HGNC id 8775
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
HOMOLOGY
Homologene
FAMILY
  • cyclic nucleotide phosphodiesterase family
    • CATEGORY enzyme
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,cytoplasm
    basic FUNCTION
  • regulates cGMP and plays a lesser role in cAMP regulation in response to cyclase agonists
  • plays a role in differentiated macrophages by regulating agonist-stimulated cGMP levels
  • may have a regulatory role in multiple immune cell types
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS