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FLASH GENE
Symbol MAFF contributors: mct/npt - updated : 04-06-2008
HGNC name v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
HGNC id 6780
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an extended leucine zipper structure but without transactivation domain
  • a heptad-leucine repeat motif (viz., Leu-zipper) that may mediate protein-protein interactions to regulate transcriptional activities
    • HOMOLOGY
    Homologene
    FAMILY
  • V-maf musculoaponeurotic fibrosarcoma (ovarian) oncogene family protein F
    • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • binds to the oxytocin receptor (myometrium)
  • plays crucial roles in the control of gene expression and development
  • may be playing a specific role in proinflammatory cytokine-mediated control of myometrial gene expression
    • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with MIP (activated transcription efficiently)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS