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FLASH GENE
Symbol MAFF contributors: mct/npt - updated : 04-06-2008
HGNC name v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
HGNC id 6780
RNA
TRANSCRIPTS type messenger
text Variants 1 and 2 encode the same protein
identificationnb exonstypebpproduct
ProteinkDaAAspecific expressionYearPubmed
3 - 2382 17.7 164 - Ye (2006)
3 - 2332 17.7 164 - Ye (2006)
EXPRESSION
Type widely
constitutive of
   expressed in (based on citations)
organ(s)
SystemOrgan level 1Organ level 2Organ level 3Organ level 4LevelPubmedSpeciesStageRna symbol
Reproductivefemale systembreastmammary gland highly
 female systemplacenta  highly
Urinarybladder   highly
 kidney    
cell lineage
cell lines
fluid/secretion
at STAGE
physiological period pregnancy
Text in term, myometrium
PROTEIN
PHYSICAL PROPERTIES
STRUCTURE
motifs/domains
  • an extended leucine zipper structure but without transactivation domain
  • a heptad-leucine repeat motif (viz., Leu-zipper) that may mediate protein-protein interactions to regulate transcriptional activities
  • HOMOLOGY
    Homologene
    FAMILY
  • V-maf musculoaponeurotic fibrosarcoma (ovarian) oncogene family protein F
  • CATEGORY protooncogene
    SUBCELLULAR LOCALIZATION     intracellular
    intracellular,nucleus
    basic FUNCTION
  • binds to the oxytocin receptor (myometrium)
  • plays crucial roles in the control of gene expression and development
  • may be playing a specific role in proinflammatory cytokine-mediated control of myometrial gene expression
  • CELLULAR PROCESS
    PHYSIOLOGICAL PROCESS
    PATHWAY
    metabolism
    signaling
    a component
    INTERACTION
    DNA
    RNA
    small molecule
    protein interacting with MIP (activated transcription efficiently)
    cell & other
    REGULATION
    ASSOCIATED DISORDERS
    ANIMAL & CELL MODELS